GIS have traditionally transcended the complexity of the world by simplifying its intricacies. Like maps, GIS are an abstraction of a much more complicated reality, and one of their huge success stories has been in supporting myriad explorative schemes atop that abstraction. Nevertheless, partly because of their origins in digital cartography, GIS have developed a reliance on static representation of the world that is increasingly out-of-place with the floods of data that now capture. Measure, and frame phenomena as they unfold around us. At the CGIS, we are working to build a next-generation of GIS that integrate process models, i.e., computer models that represent the dynamic drivers of physical, human, social, environmental, and cyber-systems from their constituent components, often in ways that course across their boundaries. These functioning of these models relies heavily upon intertwining GIS into their substrate.